Description
Order HGH fragment HGH Frag(176-191) online
Formula: C78H125N23O23S2
Molecular weight: 1817.12
Peptide purity: > 98.0%
Appearance: White powder
Related substance: Total Impurities(%) ≤ 2.0%
Acetate content: ≤ 15.0%
Bacterial Endotoxins: ≤5 IU/mg
Chain:H-Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-OH
Frag 176-191, or HGH Fragment 176-191, or hG-hormone fragment 76-191, is a modified part of amino acids sequence of so called G-hormone; it possesses properties of peptides and hormones. Its molecular mass/weight is 1817.12 while its molecular formula is C78H125N23O23S2.
Studying related to this research compound began in the late 1970s when few scientists were working with the group of similar proteins to determine their functions and physical configuration; in 1978 it was hypothesized that proteins’ functionality is linked to its correct configuration in the same way as to its informational sequence. Also in 1984 clinical research it was demonstrated that Frag 176-191 due to being rich in proline and possessing such feature as high level of proteases accessibility is responsible for conformational alterations and protein binding in specific regions.
To date it has been also proven that this hG-hormone fragment can affect on adipose fat cells by increasing lipolitic activities however it is not connected with any negative changes in glucose level in bloodstream. Furthermore, even showing some G-hormone’s properties Frag 176-191 would not cause hyperglycemia since there are no hGH-receptors involved.
The (HGH fragment 176-191) is a stabilized analogue of the growth hormone-releasing factor (GRF) that induces growth hormone (GH) in a specific and physiological manner. To date studies suggest that (HGH fragment 176-191) has several beneficial features: it reduces abdominal fat (in particular visceral fat), without compromising glycemic control (blood glucose), it increases muscle mass and improves the lipid profile. These characteristics make it an ideal candidate for the treatment of excess abdominal fat, an important aspect of HIV-associated lipodystrophy.
At a dosage of 500mcg the (HGH fragment 176-191) was shown to increase lipolytic activity in adipose tissue. In other words this fragment potently burns body fat, especially stubborn adipose body fat, and it does so potently! Of significance, is that the fragment has no negative impact on insulin sensitivity, a stark contrast from its Human Growth Hormone counterpart.(Ng FM, Sun J,Sharma L, Libinaka R, Jiang WJ, and Gianello R 2000).
Not only does the (HGH fragment 176-191) not interfere with the body’s natural insulin regulation as Human Growth Hormone can, the (HGH fragment 176-191) does not result in cellular proliferation as Human Growth Hormone does. The fragment is similar to Human Growth Hormone, hence the shared amino acid sequence, however, the (HGH fragment 176-191) does not induce hyperglycaemia or reduce insulin secretion. The (HGH fragment 176-191) does not compete for the hGH receptor and nor does it induce cell proliferation, unlike Human Growth Hormone. (Wu Z, Ng FM. 1993). Thusly, this is a very beneficial peptide in terms of burning fat, without unwanted and undesirable side effects. Of particular note is the fragments ability to increase IGF-1 levels which translate into the fragments ability to give collateral anti-aging and anabolic effects along with its ability to induce lipplytic (fat burning) activity.
In yet another study, the (HGH fragment 176-191) exhibits the ability to burn through adipose tissue by increasing lipolytic activity (the breakdown of fat) , in the most stubborn body fat (adipose tissue) while increasing energy expenditure and glucose and fat oxidation in ob/ob mice treated with (HGH fragment 176-191). In addition, (HGH fragment 176-191) increased in vitro lipolytic activity and decreased lipogenic activity in isolated adipose tissue from obese rodents and humans.(Heffernan MA, Jiang WJ, Thorburn AW, Ng FM. 2000).
Thusly, the (HGH fragment 176-191) exhibits the ability to burn through stubborn adipose tissue, while increasing energy expenditure, muscle mass, and fat oxidation. All studies have pointed to the fact that the fragment is an effective treatment for obesity and fat loss, and much safer than its Human Growth Hormone counterpart.
Includes Sodium Chloride for Dilution, all vials are dosed at 2mg (2000mcg).
Packing can be customized according to customer’s request
