Sermorelin

$19.00

Sermorelin  is measured on mg

2mg/vial

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Description

Order Sermorelin online

 

Sermorelin is a form of Growth Releasing Factor (GRF) that contains only the first 29 amino acids. GRF that is produced by neurosecretory neurons in the brain contains 44 amino acids. When the structure of GRF was first described by the Nobel Laureates, R. Guilleman and A. Shalley in the 1970’s one of their students, William Wehrenberg sought to determine which part of the molecule was essential for its pituitary stimulating action. By eliminating individual amino acids and then testing the remaining peptide, he found that only the first 29 amino acids are responsible for stimulating pituitary production and secretion of hGH.

Scientists have been studying this group of peptides for many years, starting since 1980 when doctor D. Rudman was testing this compound as a tool for anti-ageing processes and doctor William Wehrenberg was looking at different peptides and particularly GHRh to identify which part of it is needed for pituitary gland stimulating response; he eliminated single amino acids to examine peptide and that found that only 29-acids-chain was responsible for pituitary stimulation. In 1999 researchers Goa and Prakash checked sermorelin GH as provocative tasting method for deficiency of endogenous G-hormone.

The most known features of this research compound are increasing lean muscular tissue mass, reducing fat, increasing bone tissue density and even enhancing functioning of immune system. It complies with certain amino-segment of natural long-chained GHrh. Sermorelin helps to convert exceeded volume of GH by liver into IGF-1.

 

Chemical and Physical Properties

[CAS number]86168-78-7

[Synonyms]
Sermorelin [INN:BAN]
Somatoliberin (human pancreatic islet), 29-L-argininamide-30-de-L-glutamine-31-de-L-glutamine-32-deglycine-33-de-L-glutamic acid-34-de-L-serine-35-de-L-asparagine-36-de-L-glutamine-37-de-L-glutamic acid-38-de-L-arginine-39-deglycine-40-de-L-alanine-41-de-L-arginine-42-de-L-alanine-43-de-L-argininyl-44-de-L-leucinamide
Sermorelina
Sermorelina [Spanish]
Sermoreline
Sermoreline [French]
Sermorelinum
Sermorelinum [Latin]
UNII-89243S03TE
[Molecular Formula]C149H246N44O42S
[Molecular Weight]3357.88

Peptide purity: > 98.0%

Appearance: White powder
Related substance: Total Impurities(%) ≤ 2.0%
Acetate content: ≤ 15.0%
Bacterial Endotoxins: ≤5 IU/mg
[Inchi]
InChI=1/C149H246N44O42S/c1-20-77(13)116(191-122(211)81(17)168-132(221)104(66-113(204)205)178-121(210)79(15)167-123(212)88(152)62-84-39-43-86(198)44-40-84)145(234)185-102(63-83-32-23-22-24-33-83)138(227)193-118(82(18)197)146(235)186-103(65-111(155)202)137(226)189-108(71-196)142(231)182-101(64-85-41-45-87(199)46-42-85)136(225)175-93(38-31-56-165-149(161)162)126(215)174-91(35-26-28-53-151)131(220)190-115(76(11)12)143(232)184-97(58-72(3)4)124(213)166-68-112(203)170-94(47-49-109(153)200)128(217)180-100(61-75(9)10)135(224)188-106(69-194)140(229)169-80(16)120(209)172-92(37-30-55-164-148(159)160)125(214)173-90(34-25-27-52-150)127(216)179-99(60-74(7)8)134(223)181-98(59-73(5)6)133(222)176-95(48-50-110(154)201)129(218)183-105(67-114(206)207)139(228)192-117(78(14)21-2)144(233)177-96(51-57-236-19)130(219)187-107(70-195)141(230)171-89(119(156)208)36-29-54-163-147(157)158/h22-24,32-33,39-46,72-82,88-108,115-118,194-199H,20-21,25-31,34-38,47-71,150-152H2,1-19H3,(H2,153,200)(H2,154,201)(H2,155,202)(H2,156,208)(H,166,213)(H,167,212)(H,168,221)(H,169,229)(H,170,203)(H,171,230)(H,172,209)(H,173,214)(H,174,215)(H,175,225)(H,176,222)(H,177,233)(H,178,210)(H,179,216)(H,180,217)(H,181,223)(H,182,231)(H,183,218)(H,184,232)(H,185,234)(H,186,235)(H,187,219)(H,188,224)(H,189,226)(H,190,220)(H,191,211)(H,192,228)(H,193,227)(H,204,205)(H,206,207)(H4,157,158,163)(H4,159,160,164)(H4,161,162,165)
[Canonical SMILES]
CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(CO)C

(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C

(=O)NCC(=O)NC(CCC(=O)N)C(=O)

NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)

NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C(C)CC)C

(=O)NC(CCSC)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C

(=O)N)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(CC3=CC=C(C=C3)O)N

[Appearance]White powder

[Density]1.45 g/cm3
[Refractive Index]1.649
[Storage temp]20°C
[Computed Properties]
Molecular Weight:3357.96 [g/mol]
Molecular Formula:C149H246N44O42S
XLogP3-AA:-12.1
H-Bond Donor:52
H-Bond Acceptor:49
Rotatable Bond Count:118
Tautomer Count:1001
Exact Mass:3356.822054
MonoIsotopic Mass:3355.818699
Topological Polar Surface Area:1470
Heavy Atom Count:236
Formal Charge:0
Complexity:7640
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:31
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1

 

 

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